| 1) Agaricus blazei
- 58.5% Beta-Glucans (1-6, D-Beta Glucan). Many
scientists believe that the active ingredients
in Agaricus blazei are more potent than that of
any other mushrooms. It has shown real promise
as an immunomodulator and a defense against
tumors. •
Name: Also known as Murrill’s
agaricus, Royal sun agaricus, and, less
frequently, geesongrong and almond-flavored
portobello.
•
Description: Range in color from
off-white to light brown; the caps emerge as
round “buttons” from the soil and grow in size
from one to 12 inches across, depending on the
strain. At first, the gills are off-white, but
within days they turn pink, purple, and then
black.
•
Habitat: Originally from a small
mountain town in Brazil called Piedade, located
120 miles southeast of São Paulo; grows in the
southeastern United States, although not as
prolifically as in South America. It is closely
related to the North American Agaricus
subrufescens, which may turn out to be the same
species; this in turn may be good news, since
this species is cultivated and
available fresh at some local markets in the
U.S.
•
Active ingredients:
Beta-(1-3)-D-glucan; beta-(1-4)-a-D-glucan;
beta-(1-6)-D-glucan; RNA-protein complex;
glucomannan.
• Uses:
Increases production of interferon and
interleukins; fights cancer metastases (uterus);
reduces high blood pressure, blood glucose,
cholesterol levels, and the effects of
arteriosclerosis; anti-inflammatory and
anti-allergic.
2) Cordyceps sinensis
(hybridized)-
30% Beta-Glucans plus Deoxyadenosine and other
nucleosides). The wonders of Cordyceps sinensis
have been known in China for at least 1,000
years, where the mushroom is recognized as a
national medicinal treasure, a precious and
virtually sacred tonic. As a health supplement,
it is known to increase energy and vitality. •
Name: The Latin etymology of Cordyceps sinensis
is as follows: cord means “club,” ceps means
“head,” and sinensis means “Chinese.” The
mushroom is also called the “caterpillar fungus”
on account of its origin, and, less frequently,
“winter worm, summer grass.”
•
Description: The mycelium is encased in
the mummified body of the caterpillar, from
which the fungus germinates. The fruit-body is
capless, shaped like a blade or twig, dark brown
at the base, and black at the top.
•
Habitat: Cordyceps is found in the
mountains of Tibet, as low as 14,000 feet and up
to 21,000 feet high. Interviews with a number of
local collectors suggest that none had ever seen
it lower than the tree line, which is now around
14,000 in Tibet. It is usually found starting
about 500 feet higher than the tree line. It may
grow lower in Bhutan or Nepal, but in any case,
it does grow above the 14,000 foot limit. It
grows in the alpine meadows of the Himalayas and
other high mountain ranges of China, Tibet, and
Nepal.
•
Active ingredients: Polysaccharides;
deoxy-nucleosides (Cordycepin); other altered
nucleosides such as hydroxy-ethyladenosine,
which are antiviral and thought to work by a
different mechanism than the deoxy-nucleosides.
• Uses:
Anti-asthma and bronchitis; controls
atherosclerosis (cardiovascular disease); lowers
cholesterol; safely and effectively controls
arrhythmias; helps control diabetes; antiviral
(HIV, HBV); prevents liver cirrhosis
(post-hepatitis); increases stamina and fights
fatigue; increases libido and sperm count.
3) Maitake (Grifola
frondosa)
- 28% Beta-Glucans (Protien bound Fraction
extracted according to Dr. Nanba's original
formula). Maitake is a delicious culinary
mushroom but is also valued for its medicinal
properties. Traditionally, maitake was used in
Japan as a tonic to boost the immune system and
increase vitality, and the mushroom was
purported to prevent cancer and high blood
pressure.
`• Name:
Latin name, Grifola frondosa: Grifola is the
name of a fungus found in Italy; frondosa means
“leaflike.” Maitake means “dancing mushroom” in
Japanese; also known as “Hen of the Woods” and
“Sheep’s Head.”
•
Description: Grows in clusters; the
caps, which are typically 4–5 inches across,
overlap to form a sort of clump. A typical
maitake cluster is the size of a volleyball.
•
Habitat: Maitake grows at the base of
oak trees, beeches, and other dead or dying
hardwoods. Favors temperate northern forests;
indigenous to northeast Japan, Europe, Asia, and
the eastern side of the North American
continent.
•
Active ingredients: Beta-glucans,
fractions D and MD; Grifon-D. • Uses: Helps
control diabetes; helps lose weight; lowers HDL
(“bad”) cholesterol; anti-HIV; helps control
high blood pressure; anti-prostate and bladder
cancer; protects the liver; immunomodulator.
4) Shiitake (Lentinus
edodes)
- 40 % Beta-Glucans (including Lentinan and the
Alpha-Glucan KS-2). After the white button
mushroom, shiitake is the most popular culinary
mushroom in the world. The mushroom’s meaty
flavor can complement almost any dish and, as it
turns out, the mushroom that delights so many
with its distinctive flavor is also a medicinal
mushroom.
• Name:
Latin name, Lentinula edodes: lent means
“supple,” inus means “resembling,” and edodes
means “edible.” Shiitake comes from the Japanese
word for a variety of chestnut tree, shita, and
the word for mushroom, take. Sometimes called
the “Forest Mushroom” and the “Black Forest
Mushroom.” In China, known as Shaingugu (or
Shiang-ku), which means “fragrant mushroom.” The
name may derive from the Shii tree, Japanese for
“oak”; the name shiitake would therefore mean
“oak mushroom.”
•
Description: Cap is dark brown at first
and grows lighter with age; spores are white and
the edges of the gills are serrated.
•
Habitat: Shiitake grows on dead or
dying hardwood trees (chestnut, beech, oak,
Japanese alder, mulberry, and others), during
the winter and spring. Native to Japan, China,
the Korean peninsula, and other areas of East
Asia.
•
Active ingredients: 1-3 beta-glucans;
polysaccharide KS-2; glycoproteins (LEM, LAP);
eritadenine; iron, niacin, vitamins B1 and B2.
• Uses:
Major anti-cancer agent in Japan (Lentinan®);
anti-viral (HBV, HIV); anti-bacterial (strep
throat; fights caries); protects the liver;
lowers cholesterol; helps control high blood
pressure.
5) Coriolus versicolor
- 40% Beta-Glucans (including polysaccharides P
and K). Coriolus versicolor was first recorded
during the Ming Dynasty of China3, and
subsequently in a 1965 Japanese report of a
patient with stomach cancer who benefited from
drinking a tea, Saru-no-koshikake, that
contained this mushroom. Subsequent laboratory
and animal research identified the source of the
tea’s anti-tumor effects to be two
polysaccharides.
Laboratory and
animal studies have further defined the
antitumor, antimicrobial, antiviral and immune
enhancing properties in both PSK and another
protein-bound polysaccharide known as
polysaccharide-protein complex (PSPC or PSP).
Prevention and cancer control properties of PSK
have been associated with its antioxidant and
free radical scavenging properties in vitro and
in vivo. PSK has demonstrated prevention of
chemically induced DNA damage (sister chromatid
exchanges) and subsequent tumors due to
chemicals, radiation or other causes.
PSK also seems
to work in multiple steps of the malignant
process by inhibiting adhesion, invasion,
motility, and metastatic growth of tumor cells
in animal models of cancer. Adhesion and
invasion are inhibited by suppression of cell
matrix-degrading enzyme production by malignant
cells. Motility of malignant cells and
subsequent attachment to blood vessels are
inhibited by suppression of tumor-cell induced
platelet aggregation and anti-angiogenic
factors. PSK has also induced apoptosis
(programmed cell death) in lymphoma, leukemia
and pancreatic cells.
Immune
responsiveness of the host does not appear to be
affected by PSK under normal conditions, but
immune systems depressed by tumor-burden or
chemotherapy, have reportedly been restored to
normal levels by PSK in animal studies. Immune
restoration has included antibody and cytokine
production and improvement of impaired antitumor
activity of natural killer cells, T cells,
macrophages and peripheral blood lymphocytes in
vivo and in vitro. PSK has also been
demonstrated to inhibit the decline of
immunocompetence during the perioperative period
and inhibit the growth of residual tumors
following cryoablation.
A variety of
other mechanisms have been observed in
laboratory studies of PSK. It was found to alter
the expression of the p53 gene, inhibit
Epstein-Barr virus induced B-cell proliferation
and suppress heat shock proteins that are
thought to be involved in the progression of
fibrosis. PSK has also been observed to
stimulate differentiation (orderliness) of human
myeloblastic leukemic cells.
When injected
directly into a tumor, PSK produces local
inflammatory responses that result in the
non-specific killing of tumor cells9. One study
on vaccine therapy against cancer found that PSK
promotes the maturation of dendritic cells to
produce IL-12 and Th1 type cytokines; however,
another study concluded that PSK was not as
effective as OK432, a preparation of the
bacteria Streptococcus pyogenes.
References:
Ooi VE, Liu F. Immunomodulation and anti-cancer
activity of polysaccharide-protein complexes.
[Review] [179 refs]. Current Medicinal
Chemistry. 2000 Jul;7(7):715-29. The
University of
Texas M. D. Anderson Cancer Center
6) Reishi (Ganoderma
lucidum)
- 40% Beta-Glucans (1-3,{8}1-6 D- Beta Glucan,
plus Triterpenoids). Reishi has been called the
king of herbal medicines, with many herbalists
ranking it above ginseng. Although some people
use reishi to brew teas, the mushroom is usually
taken for medicinal purposes only, as it has a
very bitter, woody taste.
• Name:
Ganoderma lucidum is from the Latin word gan,
which means “shiny,” derm means “skin,” and
lucidum means “brilliant.” Also called the
“Tenthousand-year mushroom” and the “Mushroom of
immortality.”
•
Description: Most distinguishing
feature is its shiny lacquered look; has a
kidney-shaped cap and sometimes the spores
appear on the cap and give the appearance of
sandpaper. The mushroom comes in six colors: red
(akashiba), white (shiroshiba), black (kuroshiba),
blue (aoshiba), yellow (kishiba), and purple (murasakishiba).
•
Habitat: Found in dense, humid coastal
provinces of China; favors the decaying stumps
of chestnut, oak, and other broad-leaf trees.
•
Active ingredients: Beta- and
hetero-beta-glucans; ling zhi-8 protein;
ganodermic acids (triterpenes)
• Uses:
Analgesic; anti-allergic activity; expectorant
and antitussive properties;
bronchitis-preventative effect, inducing
regeneration of bronchial epithelium;
anti-inflammatory; antibacterial against
Staphylococci, Streptococci, and Streptococcus
pneumoniae; antioxidant; antitumor activity,
enhanced natural killer cell (NK) activity, and
increased production of interleukin-1 and
interleukin-2; antiviral effect; enhances bone
marrow nucleated cell proliferation; cardiotonic
action, lowering serum cholesterol levels with
no effect on triglycerides, enhancing myocardial
metabolism, and lowering blood pressure;
anti-HIV activity; general immunopotentiation.
Note: Polysaccharides are
composed of groups of interconnected
monosaccharides (single sugars) and are a
structurally diverse group that occurs widely in
nature. Unlike the nucleotides in nucleic acids
and amino acids in proteins that can only be
interconnected in one way, polysaccharides can
be interconnected at several points to form a
wide variety of branched or linear structures.
The number of possible permutations for four
different monosaccharides can be up to 35,560
unique arrangements, while four amino acids can
only form 24 different permutations. (Hodgson,
J. Biotechnology, 1991, 9, 609-613, cited
below.)
7)
Colostrum and the
Immune System:
Colostrum is an exceptional nutritional
substance that contains vital components known
to support the immune system. For centuries
colostrum has been used by most cultures for
healing and wellness. Now with research and
technology quality colostrum can be produced
with precision to ensure a pure and potent
product. HPLC: High Performance Liquid
Chromatography is a technique used in
biotechnological research as well as for the
pharmaceutical industry. Modern HPLC has many
applications including separation,
identification, purification, and quantification
of various compounds. HPLC is used to create the
optimum analysis of compounds in each batch of
colostrum to ensure efficacy.
Growth
Factors:
Proteins that bind to receptors on the cell
surface with the primary result of activating
cellular proliferation and/or differentiation.
Immunoglobulins:
Also known as antibodies, their job is to
neutralize antigens, activate complement and
promote leukocytedependent destruction of
microbes.
Interferon-y:
Its functions are important in cell-mediated
immunity against intracellular microbes. It is
predominantly responsible for the antiviral
activities of the interferons.
Interleukin-1:
One of the most important immune response
modifying interleukins. The predominant function
is to enhance the activation of T-cells in
response to allergens.
Interleukin-2:
Promotes the proliferation and differentiation
of other immune cells and potentiates apoptotic
death of antigenactivated T-cells.
Interleukin-6:
Principle function is to augment the responses
of immune cells to other cytokines. It is also
the primary inducer of the acute phase response
in the liver.
Lactoferrin:
Binds iron and competes with microorganisms for
it. Found to have antibacterial, antiviral,
antifungal, antiinflammatory, antioxidant and
immunomodulatory activities.
Lactoperoxidase:
Kills bacteria by oxidative mechanisms. When
combined with hydrogen peroxide and thiocyanate,
both of which are naturally distributed in human
tissues, it forms a potent natural antibacterial
system.
Lysozyme:
Protects us from bacterial infection. It is a
small enzyme that attacks the protective cell
walls of bacteria.
Proline-Rich
Polypeptide
(PRP): Shown to support the thymus gland, and
may help calm an overactive immune system and
stimulate an under-active immune system.
Summary
The combination
of compounds and particle reduction has resulted
in an all in one material with improved
absorbency of all relevant compounds.
60 each
300mg/capsule
Recommended 1-2 capsules per day
|
